Brasil<\/a> em posi\u00e7\u00e3o de destaque na Am\u00e9rica Latina no desenvolvimento desta terapia.<\/p>\n\n\n\nO GB221 foi desenvolvido pela empresa norte-americana Gemma Biotherapeutics, Inc. (GEMMABio). A Fiocruz, por meio do Instituto de Tecnologia em Imunobiol\u00f3gicos (Bio-Manguinhos), estabeleceu um acordo de transfer\u00eancia de tecnologia com a empresa, visando a produ\u00e7\u00e3o nacional da terapia g\u00eanica, um feito in\u00e9dito no pa\u00eds.<\/p>\n\n\n\n
Al\u00e9m disso, a estrat\u00e9gia da Fiocruz para terapias avan\u00e7adas visa capacitar o pa\u00eds com as bases necess\u00e1rias para a disponibiliza\u00e7\u00e3o destes produtos no Sistema \u00danico de Sa\u00fade (SUS). O projeto de desenvolvimento de terapias g\u00eanicas para doen\u00e7as raras, liderado pela Fiocruz, j\u00e1 recebeu investimentos de R$ 122 milh\u00f5es. <\/p>\n\n\n\n
A Financiadora de Estudos e Projetos (Finep) tamb\u00e9m contribuiu com R$ 50 milh\u00f5es para a infraestrutura de produ\u00e7\u00e3o de terapias avan\u00e7adas.<\/p>\n\n\n\n
A Bio-Manguinhos\/Fiocruz det\u00e9m a tecnologia de vetores virais, essencial para esta terapia g\u00eanica, desde a produ\u00e7\u00e3o da vacina para Covid-19.<\/p>\n\n\n\n
A iniciativa integra os esfor\u00e7os do Minist\u00e9rio da Sa\u00fade para fortalecer o Complexo Econ\u00f4mico-Industrial da Sa\u00fade (Ceis) e ampliar a Pol\u00edtica Nacional de Aten\u00e7\u00e3o \u00e0s Pessoas com Doen\u00e7as Raras, fortalecendo o SUS.<\/p>\n\n\n\n
A Atrofia Muscular Espinhal Tipo1 (AME) \u00e9 a forma mais grave da doen\u00e7a<\/h2>\n\n\n\n
A AME Tipo 1, uma doen\u00e7a rara que se manifesta nos primeiros meses de vida, \u00e9 causada por uma altera\u00e7\u00e3o no gene SMN1, respons\u00e1vel pela produ\u00e7\u00e3o de uma prote\u00edna essencial para a fun\u00e7\u00e3o dos neur\u00f4nios relacionados ao movimento. <\/p>\n\n\n\n
Por fim, a aus\u00eancia desta prote\u00edna leva \u00e0 perda progressiva da for\u00e7a muscular e pode comprometer a sobreviv\u00eancia das crian\u00e7as.<\/p>\n\n\n\n
Fonte: agenciabrasil.ebc.com.br<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"A Fiocruz recebeu autoriza\u00e7\u00e3o da Nacional de Vigil\u00e2ncia Sanit\u00e1ria (Anvisa) para iniciar testes cl\u00ednicos em humanos com Atrofia Muscular Espinhal Tipo1. A terapia g\u00eanica avan\u00e7ada […]<\/p>\n","protected":false},"author":1,"featured_media":5668,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[50,123,69,27,1476],"class_list":["post-5667","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-politica","tag-fiocruz","tag-nacional","tag-producao","tag-saude","tag-terapia"],"acf":[],"yoast_head":"\n
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